Cyberpunk tries to get away with making this horrifying by asking if you're still "human", which doesn't mean anything whatsoever. Meatpunk - in the vein of Cruelty Squad - offers the same trappings (what if you had Shotgun Arm) but asks a scarier question: what if that made your flesh company property? (The horror offered, specifically, by Cruelty Squad, is that the answer is "Yes", and there's no rolling it back)